Pair Name	Ginsenoside Rh2, Anti-PD-L1 antibody
Disease Info	[ICD-11: 2A00-2F9Z]	Solid tumour or cancer		Investigative
Biological Phenomena	Induction-->Immunomodulatory
Gene Regulation	Up-regulation	Expression	IRF1	hsa3659
	Up-regulation	Phosphorylation	IRF3	hsa3661
	Up-regulation	Phosphorylation	STAT1	hsa6772
	Up-regulation	Phosphorylation	TBK1	hsa29110
In Vitro Model	MC-38	Mouse colon adenocarcinoma	Mus musculus (Mouse)	CVCL_B288
	CT26	Mouse colon adenocarcinoma	Mus musculus (Mouse)	CVCL_7254
	4T1	Malignant neoplasms of the mouse mammary gland	Mus musculus (Mouse)	CVCL_0125
In Vivo Model	The right flank of C57BL/6 mice were received with the subcutaneous injection of 1×10⁶ MC38 cells,2.5×105 4T1 cells or 1×10⁶ CT26 cells were subcutaneously injected into the right flank of BALB/c mice.
Result	These findings demonstrated that Rh2 potentiated the anti-cancer effect of PD-L1 blockade via promoting the T cells infiltration and activation, which shed a new light on the combination strategy to enhance anti-PD-L1 immunotherapy by using natural product Rh2.